Leesburg is a city in Lake County, Florida, United States. The population was 15,956 at the 2000 census. As of 2005, the population recorded by the U.S. Census Bureau was 19,086. Leesburg is in central Florida, between Lake Harris and Lake Griffin, at the head of the Oklawaha River system. It is part of the Orlando–Kissimmee–Sanford Metropolitan Statistical Area.